How Cells Release Energy From Food
Medi stands inside a glowing mitochondrion the size of a room, holding a glucose molecule like a glowing orange gem, while tiny ATP packets light up around her like sparks flying off a campfire.
- Explain what cellular respiration is and why cells need it.
- Identify the starting materials and products of cellular respiration.
- Describe the role of the mitochondrion in releasing energy from glucose.
- Compare the energy stored in glucose with the usable energy stored in ATP.
- Predict what happens to a cell when oxygen or glucose is unavailable.
Key terms
- Cellular respiration
- The chemical process cells use to break down glucose with oxygen and release usable energy.
- Glucose
- A simple sugar from food that stores the chemical energy cells release during respiration.
- ATP
- Adenosine triphosphate, the small energy carrier that powers nearly all cellular work.
- Mitochondrion
- The organelle where most ATP is produced, with folded inner membranes called cristae.
- Glycolysis
- The first stage of respiration that breaks glucose down in the cytoplasm.
Glucose to ATP, Step by Step
Cellular respiration is a controlled disassembly of glucose, not a single explosion. It begins with glycolysis in the cytoplasm, where a glucose molecule is split into smaller pieces and a little energy is captured. Those products then enter the mitochondrion, where reactions on the folded cristae use oxygen to extract most of the remaining energy. All of that energy is repackaged into ATP, the rechargeable battery the cell can spend on muscle contraction, building molecules, and pumping ions. Carbon dioxide and water leave as harmless wastes.
Respiration Is Not Breathing
It is easy to confuse cellular respiration with breathing because they share a word, but they happen in different places. Breathing is a mechanical action that moves air in and out of the lungs and loads oxygen into the blood. Cellular respiration is a chemical reaction inside every cell that uses that oxygen to release energy from glucose. Breathing supplies a reactant for respiration, so the two cooperate, yet respiration runs constantly in every living cell, even while you sleep, because cells always need ATP.
Worked examples
Trace what happens to a muscle cell deprived of oxygen during a sprint.
- Identify the need: the muscle cell requires a steady supply of ATP to keep contracting.
- Find the source: most ATP comes from the oxygen-using reactions inside the mitochondrion.
- Remove the input: without enough oxygen, those mitochondrial reactions slow sharply.
- Predict the result: ATP production falls, so the muscle tires and the runner has to slow down.
Answer: Without oxygen the mitochondria make far less ATP, so the muscle fatigues and movement weakens.
Activity
Drag the steps of cellular respiration into the correct order from start to finish.
Practice
Write the word equation for cellular respiration and label the reactants and products.
Explain why you exhale carbon dioxide even when you are sitting completely still.
Common mistakes to avoid
- Cellular respiration and breathing are the same thingBreathing moves air in the lungs, while cellular respiration is a chemical reaction releasing energy inside cells.
- Respiration only happens during exerciseCells need ATP at all times, so respiration runs continuously, even while you rest or sleep.
Check your understanding
Which equation best represents cellular respiration?
A student says, 'Cellular respiration and breathing are the same thing.' What is wrong with this statement?
Where in the cell does most of cellular respiration take place?
Recap
Cellular respiration breaks glucose down using oxygen to package energy into ATP, with carbon dioxide and water as wastes, and it runs continuously in every cell rather than only during breathing or exercise.
Reflect
Where do you think the energy in the food you ate today actually goes inside your cells?